Tag Archives: Postpartum

Health in 2 Point 00, Episode 74 | European Money, Postpartum Care, & Social Determinants of Health

Health in 2 Point 00 Mar 22, 2019• Today on Health in 2 Point 00, Jess and I are standing on a roof answering health tech questions from the Digital Health Commercialization Panel event in San Francisco. In this episode, Jess asks me about all the money that is being raised or spent in the… Read More »

Timing of Postpartum Depression Onset May Predict Symptom Pattern

Postpartum depression (PPD) is a common and complicated illness, affecting about 15% of women in the perinatal period. Recent research from the PACT consortium (Postpartum Depression: Action Toward Causes and Treatment) has sought to classify the many potential subtypes of this heterogenous illness and has found emerging differences in time of onset, severity, comorbid anxiety,… Read More »

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »